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Shrooms kan depressie behandel - maar probeer dit nie tuis nie

Shrooms kan depressie behandel - maar probeer dit nie tuis nie


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Hierdie onwettige dwelm kan binnekort 'n medisinale middel wees

Droom tyd

Verdere navorsing is nog op hande.

Magiese sampioene, 'n psigedeliese middel, het onlangs onthul is as 'n effektiewe behandeling vir kliniese depressie. Die 'reset' verminder depressiewe simptome effektief tot vyf weke na die behandeling.

Tydens die studie is 20 pasiënte met behandelingsweerstandige depressie twee dosisse van die verbinding per week gegee. Na die eerste behandeling het pasiënte 'n afname in hul depressiewe simptome gerapporteer, wat wissel van 'n eenvoudige slaapstoornis tot oormatige huil of agitasie. Hulle gemoedstoestand het verbeter, hul spanning is verlig en MRI -skanderings het minder aktiwiteit in die brein gebiede wat verband hou met stres en vrees onthul.

Beide die binne en buite simptome is verlig - en alles wat nodig was, was 'n klein dosis sjampoe.

"Psilocybin gee hierdie individue moontlik die tydelike 'kick start' wat hulle nodig het om uit hul depressiewe toestande te breek," het dr. Robin Carhart-Harris, hoofnavorser van die studie, gesê. 'Soortgelyke breineffekte as hierdie is gesien met elektrokonvulsiewe terapie.'

'N Reis deur 'n dwelm klink na 'n baie aantrekliker opsie as traumatiese elektrokonvulsiewe terapie-maar wetenskaplikes vind dit belangrik om daarop te let dat selfmedikasie gevaarlik is en vermy moet word.

Moenie bekommerd wees nie, verdere navorsing word gedoen. Eendag is hierdie moeilike behandeling moontlik wettig. Maar as u die dwelm nou koop, sal u waarskynlik in die tronk beland en hierdie ander eet 20 natuurlike verligters van angs en depressie sal nie.


Psigedeliese 'shrooms' kan positiewe langtermyn effekte op die brein hê

Psigedeliese sampioene kan meer doen as om jou die wêreld in 'n kaleidoskoop te laat sien. Navorsing dui daarop dat dit 'n permanente, positiewe uitwerking op die menslike brein kan hê.

Trouens, 'n verstandsveranderende verbinding wat in ongeveer 200 spesies sampioene voorkom, word reeds ondersoek as 'n moontlike behandeling vir depressie en angs. Mense wat hierdie sampioene eet, na 'n bietjie angswekkend en onaangenaam, kan meer optimisties, minder selfgesentreerd en selfs gelukkiger voel vir maande daarna.

Maar waarom verander hierdie reise die manier waarop mense die wêreld sien? Volgens 'n studie wat hierdie week in Human Brain Mapping gepubliseer is, kan die sampioenverbindings breintoestande ontsluit wat gewoonlik net ondervind word as ons droom, veranderinge in aktiwiteit wat permanente verskuiwings in perspektief kan help ontsluit.

Die studie ondersoek die breinaktiwiteit by diegene wat inspuitings van psilocybine ontvang het, wat 'n psychedeliese stoot gee. Ondanks 'n lang geskiedenis van die gebruik van sampioene in geestelike praktyk, het wetenskaplikes eers onlangs begin om die breinaktiwiteit van diegene wat die verbinding gebruik, te ondersoek, en dit is die eerste studie wat probeer om die gedragseffekte met biologiese veranderinge in verband te bring.

Na die inspuitings het die 15 deelnemers 'n verhoogde breinfunksie gehad op gebiede wat met emosie en geheue verband hou. Volgens Robin Carhart-Harris, 'n postdoktorale navorser in neuropsigofarmakologie aan die Imperial College in Londen en mede-outeur van die studie, was die effek opvallend soortgelyk aan 'n brein in droom slaap.

& ldquo U sien dat hierdie gebiede harder en meer aktief word, en hy het gesê. & ldquoDit & rsquos soos iemand & rsquos het die volume daar verhoog, in hierdie streke wat as deel van 'n emosionele stelsel in die brein beskou word. As u na 'n brein kyk tydens droom slaap, sien u dieselfde hiperaktiewe emosiesentrums. & Rdquo

Trouens, dit lyk asof die toediening van die geneesmiddel net voor of tydens die slaap hoër aktiwiteitsvlakke bevorder tydens Rapid Eye Movement -slaap, wanneer drome ontstaan. 'N Interessante bevinding, sê Carhart-Harris, aangesien mense geneig is om hul ervaring met psigedeliese middels te beskryf as 'n wakker droom. & Rdquo Dit lyk asof die brein letterlik in bewustelose patrone kan gly terwyl die gebruiker wakker is.
Omgekeerd het die proefpersone van die studie verminderde aktiwiteit in ander dele van die breinareas wat verband hou met hoëvlak kognisie. Dit is in die evolusionêre sin die mees onlangse dele van ons brein, het Carhart-Harris gesê. & ldquo En ons sien hoe hulle stiller en minder georganiseerd raak. & rdquo

Hierdie demping van een gebied en versterking van 'n ander kan die sensasie van psigedeliese medisyne verklaar, 'sê hy. In teenstelling met die meeste ontspanningsmedisyne, bied psigotropiese sampioene en LSD nie 'n aangename, hedonistiese beloning as hulle eet nie. In plaas daarvan neem gebruikers dit soms af, jaag hulle na die vreemde neurologiese effekte in plaas van enige hoë.

& ldquo Behalwe vir sommige gebruikers wat op soek is na 'n goeie tyd en hellip, wat terloops nie so is nie, & rdquo Carhart-Harris gesê, & ldquoyou sien hoe mense hulle neem om 'n soort geestelike verkenning te beleef en om hulself te probeer verstaan . & rdquo

Ons vaste gevoel van self en die gewoontes en ervarings wat ons as 'n integrale deel van ons persoonlikheid vind, word stilgemaak deur hierdie reise. Carhart-Harris glo dat die dwelms emosies kan ontsluit terwyl hulle die ego basies doodmaak, sodat gebruikers minder bekrompe kan wees en negatiewe uitkyk kan laat vaar.

Dit is nog steeds nie duidelik waarom sulke gevolge 'n meer langtermyn-effek op die brein kan hê as ons nagdrome nie. Maar Carhart-Harris hoop om meer van hierdie verbindings in moderne medisyne te sien. & ldquo Die manier waarop ons sielkundige siektes nou behandel, is om dinge te demp, en hy het gesê. Ons demp angs, demp 'n mens se emosionele omvang in die hoop om depressie te genees, en verwyder die angel uit wat 'n mens voel. & rdquo
Maar sommige pasiënte baat daarby baat daarby om hul emosies in plaas daarvan te laat afsluit. & ldquo Dit pas regtig by die styl van psigoterapie waar ons deelneem aan 'n pasiënt se geskiedenis en hang-ups, & rdquo Carhart-Harris gesê. In plaas daarvan om 'n verband oor die blootgestelde wond te plaas, maak ons ​​in werklikheid hul gedagtes los en bevorder ons 'n permanente verandering in vooruitsigte. & rdquo

Die jongste navorsing dui daarop dat Psilocybin & mdash, die aktiewe bestanddeel in tower sampioene en mdash, tot 'n maand lank 'n positiewe uitwerking op die breinfunksie en emosionele gesondheid kan hê nadat dit die een -rsquos -stelsel verlaat het.

Voorheen het die meeste studies oor Psilocybin gefokus op die akute uitwerking van die stof op die gebruiker. Die studie wat deur navorsers van die Johns Hopkins University School of Medicine gedoen is, en in die tydskrif Scientific Reports gepubliseer is, het die draaiboek omgedraai en gekyk na die blywende gevolge van die psigedeliese middel.

Byna alle psigedeliese beeldingstudies is uitgevoer tydens die akute effekte van psigedeliese middels, & rdquo verduidelik Frederick S. Barrett, assistent -professor aan die Johns Hopkins University School of Medicine en die ooreenstemmende skrywer van die studie. Alhoewel akute uitwerking van psigedelika op die brein natuurlik ongelooflik interessant is, het die blywende effekte van psigedeliese middels op die breinfunksie 'n groot onbenutte waarde om ons te help om meer te verstaan ​​oor die brein, die invloed daarvan en die behandeling van psigiatriese afwykings. & rdquo

Oor die Psilocybin -studie

Die studie & mdash getiteld & lsquo Emosies en breinfunksie word tot 'n maand verander nadat 'n enkele hoë dosis Psilocybin & rsquo & mdash na 12 vrywilligers gekyk het wat elk 'n enkele dosis Psilocybin ontvang het. Die deelnemers het toetse ondergaan die dag voordat hulle die Psilocybin geneem het, 'n week nadat hulle Psilocybin geneem het en 'n maand later. Elke vrywilliger het die taak gehad om drie verskillende assesserings te voltooi wat ontwerp is om hul vermoë om emosionele inligting te verwerk (dit wil sê gesigswyses) te kwantifiseer. Terselfdertyd het die navorsingspan hul breinaktiwiteit bestudeer met behulp van 'n MRI.

Die studie het weliswaar slegs 'n klein aantal deelnemers betrek en sterk op selfrapportasie staatgemaak, maar deelnemers het 'n afname in emosionele nood in die week na die toediening van Psilocybin gerapporteer. Teen die punt van een maand het die gerapporteerde emosionele nood gewoonlik teruggekeer na die basislynvlakke.


Psigedeliese 'shrooms' kan positiewe langtermyn effekte op die brein hê

Psigedeliese sampioene kan meer doen as om jou die wêreld in 'n kaleidoskoop te laat sien. Navorsing dui daarop dat dit 'n permanente, positiewe uitwerking op die menslike brein kan hê.

Trouens, 'n verstandsveranderende verbinding wat in ongeveer 200 spesies sampioene voorkom, word reeds ondersoek as 'n moontlike behandeling vir depressie en angs. Mense wat hierdie sampioene eet, na 'n bietjie angswekkend en onaangenaam, kan meer optimisties, minder selfgesentreerd en selfs gelukkiger voel vir maande daarna.

Maar waarom verander hierdie reise die manier waarop mense die wêreld sien? Volgens 'n studie wat hierdie week in Human Brain Mapping gepubliseer is, kan die sampioenverbindings breintoestande ontsluit wat gewoonlik net ondervind word as ons droom, veranderinge in aktiwiteit wat permanente verskuiwings in perspektief kan help ontsluit.

Die studie ondersoek die breinaktiwiteit by diegene wat inspuitings van psilocybine ontvang het, wat 'n psychedeliese stoot gee. Ondanks 'n lang geskiedenis van die gebruik van sampioene in geestelike praktyk, het wetenskaplikes eers onlangs begin om die breinaktiwiteit van diegene wat die verbinding gebruik, te ondersoek, en dit is die eerste studie wat probeer om die gedragseffekte met biologiese veranderinge in verband te bring.

Na die inspuitings het die 15 deelnemers 'n verhoogde breinfunksie gehad op gebiede wat met emosie en geheue verband hou. Volgens Robin Carhart-Harris, 'n postdoktorale navorser in neuropsigofarmakologie aan die Imperial College in Londen en mede-outeur van die studie, was die effek opvallend soortgelyk aan 'n brein in droom slaap.

& ldquo U sien dat hierdie gebiede harder en meer aktief word, en hy het gesê. & ldquoDit & rsquos soos iemand & rsquos het die volume daar verhoog, in hierdie streke wat as deel van 'n emosionele stelsel in die brein beskou word. As u na 'n brein kyk tydens droom slaap, sien u dieselfde hiperaktiewe emosiesentrums. & Rdquo

Trouens, dit lyk asof die toediening van die geneesmiddel net voor of tydens die slaap hoër aktiwiteitsvlakke bevorder tydens Rapid Eye Movement -slaap, wanneer drome ontstaan. 'N Interessante bevinding, sê Carhart-Harris, aangesien mense geneig is om hul ervaring met psigedeliese middels te beskryf as 'n wakker droom. & Rdquo Dit lyk asof die brein letterlik in bewustelose patrone kan gly terwyl die gebruiker wakker is.
Omgekeerd het die proefpersone van die studie verminderde aktiwiteit in ander dele van die breinareas wat verband hou met hoëvlak kognisie. Dit is in die evolusionêre sin die mees onlangse dele van ons brein, het Carhart-Harris gesê. & ldquo En ons sien hoe hulle stiller en minder georganiseerd raak. & rdquo

Hierdie demping van een gebied en versterking van 'n ander kan die sensasie van psigedeliese medisyne verklaar, 'sê hy. In teenstelling met die meeste ontspanningsmedisyne, bied psigotropiese sampioene en LSD nie 'n aangename, hedonistiese beloning as hulle eet nie. In plaas daarvan neem gebruikers dit soms af, jaag hulle na die vreemde neurologiese effekte in plaas van enige hoë.

& ldquo Behalwe vir sommige gebruikers wat op soek is na 'n goeie tyd en hellip, wat terloops nie so is nie, & rdquo Carhart-Harris gesê, & ldquoyou sien hoe mense hulle neem om 'n soort geestelike verkenning te beleef en om hulself te probeer verstaan . & rdquo

Ons vaste gevoel van self en die gewoontes en ervarings wat ons as 'n integrale deel van ons persoonlikheid vind, word stilgemaak deur hierdie reise. Carhart-Harris glo dat die dwelms emosies kan ontsluit terwyl hulle die ego basies doodmaak, sodat gebruikers minder bekrompe kan wees en negatiewe uitkyk kan laat vaar.

Dit is nog steeds nie duidelik waarom sulke gevolge 'n meer langtermyn-effek op die brein kan hê as ons nagdrome nie. Maar Carhart-Harris hoop om meer van hierdie verbindings in moderne medisyne te sien. & ldquo Die manier waarop ons sielkundige siektes nou behandel, is om dinge te demp, en hy het gesê. Ons demp angs, demp 'n mens se emosionele omvang in die hoop om depressie te genees, en verwyder die angel uit wat 'n mens voel. & rdquo
Maar sommige pasiënte baat daarby baat daarby om hul emosies in plaas daarvan te laat afsluit. & ldquo Dit pas regtig by die styl van psigoterapie waar ons deelneem aan 'n pasiënt se geskiedenis en hang-ups, & rdquo Carhart-Harris gesê. In plaas daarvan om 'n verband oor die blootgestelde wond te plaas, maak ons ​​in werklikheid hul gedagtes los en bevorder ons 'n permanente verandering in vooruitsigte. & rdquo

Die jongste navorsing dui daarop dat Psilocybin & mdash, die aktiewe bestanddeel in tower sampioene en mdash, tot 'n maand lank 'n positiewe uitwerking op die breinfunksie en emosionele gesondheid kan hê nadat dit die een -rsquos -stelsel verlaat het.

Voorheen het die meeste studies oor Psilocybin gefokus op die akute uitwerking van die stof op die gebruiker. Die studie wat deur navorsers van die Johns Hopkins University School of Medicine gedoen is, en in die tydskrif Scientific Reports gepubliseer is, het die draaiboek omgedraai en gekyk na die blywende gevolge van die psigedeliese middel.

Byna alle psigedeliese beeldingstudies is uitgevoer tydens die akute effekte van psigedeliese middels, & rdquo verduidelik Frederick S. Barrett, assistent -professor aan die Johns Hopkins University School of Medicine en die ooreenstemmende skrywer van die studie. Alhoewel akute uitwerking van psigedelika op die brein natuurlik ongelooflik interessant is, het die blywende effekte van psigedeliese middels op die breinfunksie 'n groot onbenutte waarde om ons te help om meer te verstaan ​​oor die brein, die invloed daarvan en die behandeling van psigiatriese afwykings. & rdquo

Oor die Psilocybin -studie

Die studie & mdash getiteld & lsquo Emosies en breinfunksie word tot 'n maand verander nadat 'n enkele hoë dosis Psilocybin & rsquo & mdash na 12 vrywilligers gekyk het wat elk 'n enkele dosis Psilocybin ontvang het. Die deelnemers het toetse ondergaan die dag voordat hulle die Psilocybin geneem het, 'n week nadat hulle Psilocybin geneem het en 'n maand later. Elke vrywilliger het die taak gehad om drie verskillende assesserings te voltooi wat ontwerp is om hul vermoë om emosionele inligting te verwerk (dit wil sê gesigswyses) te kwantifiseer. Terselfdertyd het die navorsingspan hul breinaktiwiteit bestudeer met behulp van 'n MRI.

Die studie het weliswaar slegs 'n klein aantal deelnemers betrek en sterk op selfrapportasie staatgemaak, maar deelnemers het 'n afname in emosionele nood in die week na die toediening van Psilocybin gerapporteer. Teen die punt van een maand het die gerapporteerde emosionele nood gewoonlik teruggekeer na die basislynvlakke.


Psigedeliese 'shrooms' kan positiewe langtermyn effekte op die brein hê

Psigedeliese sampioene kan meer doen as om jou die wêreld in 'n kaleidoskoop te laat sien. Navorsing dui daarop dat dit 'n permanente, positiewe uitwerking op die menslike brein kan hê.

Trouens, 'n verstandsveranderende verbinding wat in ongeveer 200 spesies sampioene voorkom, word reeds ondersoek as 'n moontlike behandeling vir depressie en angs. Mense wat hierdie sampioene eet, na 'n bietjie angswekkend en onaangenaam, kan meer optimisties, minder selfgesentreerd en selfs gelukkiger voel vir maande daarna.

Maar waarom verander hierdie reise die manier waarop mense die wêreld sien? Volgens 'n studie wat hierdie week in Human Brain Mapping gepubliseer is, kan die sampioenverbindings breintoestande ontsluit wat gewoonlik net ondervind word as ons droom, veranderinge in aktiwiteit wat permanente verskuiwings in perspektief kan help ontsluit.

Die studie ondersoek die breinaktiwiteit by diegene wat inspuitings van psilocybine ontvang het, wat 'n psychedeliese stoot gee. Ondanks 'n lang geskiedenis van die gebruik van sampioene in geestelike praktyk, het wetenskaplikes eers onlangs begin om die breinaktiwiteit van diegene wat die verbinding gebruik, te ondersoek, en dit is die eerste studie wat probeer om die gedragseffekte met biologiese veranderinge in verband te bring.

Na die inspuitings het die 15 deelnemers 'n verhoogde breinfunksie gehad op gebiede wat met emosie en geheue verband hou. Volgens Robin Carhart-Harris, 'n postdoktorale navorser in neuropsigofarmakologie aan die Imperial College in Londen en mede-outeur van die studie, was die effek opvallend soortgelyk aan 'n brein in droom slaap.

& ldquo U sien dat hierdie gebiede harder en meer aktief word, en hy het gesê. & ldquoDit & rsquos soos iemand & rsquos het die volume daar verhoog, in hierdie streke wat as deel van 'n emosionele stelsel in die brein beskou word. As u na 'n brein kyk tydens droom slaap, sien u dieselfde hiperaktiewe emosiesentrums. & Rdquo

Trouens, dit lyk asof die toediening van die geneesmiddel net voor of tydens die slaap hoër aktiwiteitsvlakke bevorder tydens Rapid Eye Movement -slaap, wanneer drome ontstaan. 'N Interessante bevinding, sê Carhart-Harris, aangesien mense geneig is om hul ervaring met psigedeliese middels te beskryf as 'n wakker droom. & Rdquo Dit lyk asof die brein letterlik in bewustelose patrone kan gly terwyl die gebruiker wakker is.
Omgekeerd het die proefpersone van die studie verminderde aktiwiteit in ander dele van die breinareas wat verband hou met hoëvlak kognisie. Dit is in die evolusionêre sin die mees onlangse dele van ons brein, het Carhart-Harris gesê. & ldquo En ons sien hoe hulle stiller en minder georganiseerd raak. & rdquo

Hierdie demping van een gebied en versterking van 'n ander kan die sensasie van psigedeliese medisyne verklaar, 'sê hy. In teenstelling met die meeste ontspanningsmedisyne, bied psigotropiese sampioene en LSD nie 'n aangename, hedonistiese beloning as hulle eet nie. In plaas daarvan neem gebruikers dit soms af, jaag hulle na die vreemde neurologiese effekte in plaas van enige hoë.

& ldquo Behalwe vir sommige gebruikers wat op soek is na 'n goeie tyd en hellip, wat terloops nie so is nie, & rdquo Carhart-Harris gesê, & ldquoyou sien hoe mense hulle neem om 'n soort geestelike verkenning te beleef en om hulself te probeer verstaan . & rdquo

Ons vaste gevoel van self en die gewoontes en ervarings wat ons as 'n integrale deel van ons persoonlikheid vind, word stilgemaak deur hierdie reise. Carhart-Harris glo dat die dwelms emosies kan ontsluit terwyl hulle die ego basies doodmaak, sodat gebruikers minder bekrompe kan wees en negatiewe uitkyk kan laat vaar.

Dit is nog steeds nie duidelik waarom sulke gevolge 'n meer langtermyn-effek op die brein kan hê as ons nagdrome nie. Maar Carhart-Harris hoop om meer van hierdie verbindings in moderne medisyne te sien. & ldquo Die manier waarop ons sielkundige siektes nou behandel, is om dinge te demp, en hy het gesê. Ons demp angs, demp 'n mens se emosionele omvang in die hoop om depressie te genees, en verwyder die angel uit wat 'n mens voel. & rdquo
Maar sommige pasiënte baat daarby baat daarby om hul emosies in plaas daarvan te laat afsluit. & ldquo Dit pas regtig by die styl van psigoterapie waar ons deelneem aan 'n pasiënt se geskiedenis en hang-ups, & rdquo Carhart-Harris gesê. In plaas daarvan om 'n verband oor die blootgestelde wond te plaas, maak ons ​​in werklikheid hul gedagtes los en bevorder ons 'n permanente verandering in vooruitsigte. & rdquo

Die jongste navorsing dui daarop dat Psilocybin & mdash, die aktiewe bestanddeel in tower sampioene en mdash, tot 'n maand lank 'n positiewe uitwerking op die breinfunksie en emosionele gesondheid kan hê nadat dit die een -rsquos -stelsel verlaat het.

Voorheen het die meeste studies oor Psilocybin gefokus op die akute uitwerking van die stof op die gebruiker. Die studie wat deur navorsers van die Johns Hopkins University School of Medicine gedoen is, en in die tydskrif Scientific Reports gepubliseer is, het die draaiboek omgedraai en gekyk na die blywende gevolge van die psigedeliese middel.

Byna alle psigedeliese beeldingstudies is uitgevoer tydens die akute effekte van psigedeliese middels, & rdquo verduidelik Frederick S. Barrett, assistent -professor aan die Johns Hopkins University School of Medicine en die ooreenstemmende skrywer van die studie. Alhoewel akute uitwerking van psigedelika op die brein natuurlik ongelooflik interessant is, het die blywende effekte van psigedeliese middels op die breinfunksie 'n groot onbenutte waarde om ons te help om meer te verstaan ​​oor die brein, die invloed daarvan en die behandeling van psigiatriese afwykings. & rdquo

Oor die Psilocybin -studie

Die studie & mdash getiteld & lsquo Emosies en breinfunksie word tot 'n maand verander nadat 'n enkele hoë dosis Psilocybin & rsquo & mdash na 12 vrywilligers gekyk het wat elk 'n enkele dosis Psilocybin ontvang het. Die deelnemers het toetse ondergaan die dag voordat hulle die Psilocybin geneem het, 'n week nadat hulle Psilocybin geneem het en 'n maand later. Elke vrywilliger het die taak gehad om drie verskillende assesserings te voltooi wat ontwerp is om hul vermoë om emosionele inligting te verwerk (dit wil sê gesigswyses) te kwantifiseer. Terselfdertyd het die navorsingspan hul breinaktiwiteit bestudeer met behulp van 'n MRI.

Die studie het weliswaar slegs 'n klein aantal deelnemers betrek en sterk op selfrapportasie staatgemaak, maar deelnemers het 'n afname in emosionele nood in die week na die toediening van Psilocybin gerapporteer. Teen die punt van een maand het die gerapporteerde emosionele nood gewoonlik teruggekeer na die basislynvlakke.


Psigedeliese 'shrooms' kan positiewe langtermyn effekte op die brein hê

Psigedeliese sampioene kan meer doen as om jou die wêreld in 'n kaleidoskoop te laat sien. Navorsing dui daarop dat dit 'n permanente, positiewe uitwerking op die menslike brein kan hê.

Trouens, 'n verstandsveranderende verbinding wat in ongeveer 200 spesies sampioene voorkom, word reeds ondersoek as 'n moontlike behandeling vir depressie en angs. Mense wat hierdie sampioene eet, na 'n bietjie angswekkend en onaangenaam, kan meer optimisties, minder selfgesentreerd en selfs gelukkiger voel vir maande daarna.

Maar waarom verander hierdie reise die manier waarop mense die wêreld sien? Volgens 'n studie wat hierdie week in Human Brain Mapping gepubliseer is, kan die sampioenverbindings breintoestande ontsluit wat gewoonlik net ondervind word as ons droom, veranderinge in aktiwiteit wat permanente verskuiwings in perspektief kan help ontsluit.

Die studie ondersoek die breinaktiwiteit by diegene wat inspuitings van psilocybine ontvang het, wat 'n psychedeliese stoot gee. Ondanks 'n lang geskiedenis van die gebruik van sampioene in geestelike praktyk, het wetenskaplikes eers onlangs begin om die breinaktiwiteit van diegene wat die verbinding gebruik, te ondersoek, en dit is die eerste studie wat probeer om die gedragseffekte met biologiese veranderinge in verband te bring.

Na die inspuitings het die 15 deelnemers 'n verhoogde breinfunksie gehad op gebiede wat met emosie en geheue verband hou. Volgens Robin Carhart-Harris, 'n postdoktorale navorser in neuropsigofarmakologie aan die Imperial College in Londen en mede-outeur van die studie, was die effek opvallend soortgelyk aan 'n brein in droom slaap.

& ldquo U sien dat hierdie gebiede harder en meer aktief word, en hy het gesê. & ldquoDit & rsquos soos iemand & rsquos het die volume daar verhoog, in hierdie streke wat as deel van 'n emosionele stelsel in die brein beskou word. As u na 'n brein kyk tydens droom slaap, sien u dieselfde hiperaktiewe emosiesentrums. & Rdquo

Trouens, dit lyk asof die toediening van die geneesmiddel net voor of tydens die slaap hoër aktiwiteitsvlakke bevorder tydens Rapid Eye Movement -slaap, wanneer drome ontstaan. 'N Interessante bevinding, sê Carhart-Harris, aangesien mense geneig is om hul ervaring met psigedeliese middels te beskryf as 'n wakker droom. & Rdquo Dit lyk asof die brein letterlik in bewustelose patrone kan gly terwyl die gebruiker wakker is.
Omgekeerd het die proefpersone van die studie verminderde aktiwiteit in ander dele van die breinareas wat verband hou met hoëvlak kognisie. Dit is in die evolusionêre sin die mees onlangse dele van ons brein, het Carhart-Harris gesê. & ldquo En ons sien hoe hulle stiller en minder georganiseerd raak. & rdquo

Hierdie demping van een gebied en versterking van 'n ander kan die sensasie van psigedeliese medisyne verklaar, 'sê hy. In teenstelling met die meeste ontspanningsmedisyne, bied psigotropiese sampioene en LSD nie 'n aangename, hedonistiese beloning as hulle eet nie. In plaas daarvan neem gebruikers dit soms af, jaag hulle na die vreemde neurologiese effekte in plaas van enige hoë.

& ldquo Behalwe vir sommige gebruikers wat op soek is na 'n goeie tyd en hellip, wat terloops nie so is nie, & rdquo Carhart-Harris gesê, & ldquoyou sien hoe mense hulle neem om 'n soort geestelike verkenning te beleef en om hulself te probeer verstaan . & rdquo

Ons vaste gevoel van self en die gewoontes en ervarings wat ons as 'n integrale deel van ons persoonlikheid vind, word stilgemaak deur hierdie reise. Carhart-Harris glo dat die dwelms emosies kan ontsluit terwyl hulle die ego basies doodmaak, sodat gebruikers minder bekrompe kan wees en negatiewe uitkyk kan laat vaar.

Dit is nog steeds nie duidelik waarom sulke gevolge 'n meer langtermyn-effek op die brein kan hê as ons nagdrome nie. Maar Carhart-Harris hoop om meer van hierdie verbindings in moderne medisyne te sien. & ldquo Die manier waarop ons sielkundige siektes nou behandel, is om dinge te demp, en hy het gesê. Ons demp angs, demp 'n mens se emosionele omvang in die hoop om depressie te genees, en verwyder die angel uit wat 'n mens voel. & rdquo
Maar sommige pasiënte baat daarby baat daarby om hul emosies in plaas daarvan te laat afsluit. & ldquo Dit pas regtig by die styl van psigoterapie waar ons deelneem aan 'n pasiënt se geskiedenis en hang-ups, & rdquo Carhart-Harris gesê. In plaas daarvan om 'n verband oor die blootgestelde wond te plaas, maak ons ​​in werklikheid hul gedagtes los en bevorder ons 'n permanente verandering in vooruitsigte. & rdquo

Die jongste navorsing dui daarop dat Psilocybin & mdash, die aktiewe bestanddeel in tower sampioene en mdash, tot 'n maand lank 'n positiewe uitwerking op die breinfunksie en emosionele gesondheid kan hê nadat dit die een -rsquos -stelsel verlaat het.

Voorheen het die meeste studies oor Psilocybin gefokus op die akute uitwerking van die stof op die gebruiker. Die studie wat deur navorsers van die Johns Hopkins University School of Medicine gedoen is, en in die tydskrif Scientific Reports gepubliseer is, het die draaiboek omgedraai en gekyk na die blywende gevolge van die psigedeliese middel.

Byna alle psigedeliese beeldingstudies is uitgevoer tydens die akute effekte van psigedeliese middels, & rdquo verduidelik Frederick S. Barrett, assistent -professor aan die Johns Hopkins University School of Medicine en die ooreenstemmende skrywer van die studie. Alhoewel akute uitwerking van psigedelika op die brein natuurlik ongelooflik interessant is, het die blywende effekte van psigedeliese middels op die breinfunksie 'n groot onbenutte waarde om ons te help om meer te verstaan ​​oor die brein, die invloed daarvan en die behandeling van psigiatriese afwykings. & rdquo

Oor die Psilocybin -studie

Die studie & mdash getiteld & lsquo Emosies en breinfunksie word tot 'n maand verander nadat 'n enkele hoë dosis Psilocybin & rsquo & mdash na 12 vrywilligers gekyk het wat elk 'n enkele dosis Psilocybin ontvang het. Die deelnemers het toetse ondergaan die dag voordat hulle die Psilocybin geneem het, 'n week nadat hulle Psilocybin geneem het en 'n maand later. Elke vrywilliger het die taak gehad om drie verskillende assesserings te voltooi wat ontwerp is om hul vermoë om emosionele inligting te verwerk (dit wil sê gesigswyses) te kwantifiseer. Terselfdertyd het die navorsingspan hul breinaktiwiteit bestudeer met behulp van 'n MRI.

Die studie het weliswaar slegs 'n klein aantal deelnemers betrek en sterk op selfrapportasie staatgemaak, maar deelnemers het 'n afname in emosionele nood in die week na die toediening van Psilocybin gerapporteer. Teen die punt van een maand het die gerapporteerde emosionele nood gewoonlik teruggekeer na die basislynvlakke.


Psigedeliese 'shrooms' kan positiewe langtermyn effekte op die brein hê

Psigedeliese sampioene kan meer doen as om jou die wêreld in 'n kaleidoskoop te laat sien. Navorsing dui daarop dat dit 'n permanente, positiewe uitwerking op die menslike brein kan hê.

Trouens, 'n verstandsveranderende verbinding wat in ongeveer 200 spesies sampioene voorkom, word reeds ondersoek as 'n moontlike behandeling vir depressie en angs. Mense wat hierdie sampioene eet, na 'n bietjie angswekkend en onaangenaam, kan meer optimisties, minder selfgesentreerd en selfs gelukkiger voel vir maande daarna.

Maar waarom verander hierdie reise die manier waarop mense die wêreld sien? Volgens 'n studie wat hierdie week in Human Brain Mapping gepubliseer is, kan die sampioenverbindings breintoestande ontsluit wat gewoonlik net ondervind word as ons droom, veranderinge in aktiwiteit wat permanente verskuiwings in perspektief kan help ontsluit.

Die studie ondersoek die breinaktiwiteit by diegene wat inspuitings van psilocybine ontvang het, wat 'n psychedeliese stoot gee. Ondanks 'n lang geskiedenis van die gebruik van sampioene in geestelike praktyk, het wetenskaplikes eers onlangs begin om die breinaktiwiteit van diegene wat die verbinding gebruik, te ondersoek, en dit is die eerste studie wat probeer om die gedragseffekte met biologiese veranderinge in verband te bring.

Na die inspuitings het die 15 deelnemers 'n verhoogde breinfunksie gehad op gebiede wat met emosie en geheue verband hou. Volgens Robin Carhart-Harris, 'n postdoktorale navorser in neuropsigofarmakologie aan die Imperial College in Londen en mede-outeur van die studie, was die effek opvallend soortgelyk aan 'n brein in droom slaap.

& ldquo U sien dat hierdie gebiede harder en meer aktief word, en hy het gesê. & ldquoDit & rsquos soos iemand & rsquos het die volume daar verhoog, in hierdie streke wat as deel van 'n emosionele stelsel in die brein beskou word. As u na 'n brein kyk tydens droom slaap, sien u dieselfde hiperaktiewe emosiesentrums. & Rdquo

Trouens, dit lyk asof die toediening van die geneesmiddel net voor of tydens die slaap hoër aktiwiteitsvlakke bevorder tydens Rapid Eye Movement -slaap, wanneer drome ontstaan. 'N Interessante bevinding, sê Carhart-Harris, aangesien mense geneig is om hul ervaring met psigedeliese middels te beskryf as 'n wakker droom. & Rdquo Dit lyk asof die brein letterlik in bewustelose patrone kan gly terwyl die gebruiker wakker is.
Omgekeerd het die proefpersone van die studie verminderde aktiwiteit in ander dele van die breinareas wat verband hou met hoëvlak kognisie. Dit is in die evolusionêre sin die mees onlangse dele van ons brein, het Carhart-Harris gesê. & ldquo En ons sien hoe hulle stiller en minder georganiseerd raak. & rdquo

Hierdie demping van een gebied en versterking van 'n ander kan die sensasie van psigedeliese medisyne verklaar, 'sê hy. In teenstelling met die meeste ontspanningsmedisyne, bied psigotropiese sampioene en LSD nie 'n aangename, hedonistiese beloning as hulle eet nie. In plaas daarvan neem gebruikers dit soms af, jaag hulle na die vreemde neurologiese effekte in plaas van enige hoë.

&ldquoExcept for some naïve users who go looking for a good time &hellip which, by the way, is not how it plays out,&rdquo Carhart-Harris said, &ldquoyou see people taking them to experience some kind of mental exploration and to try to understand themselves.&rdquo

Our firm sense of self &mdash the habits and experiences that we find integral to our personality &mdash is quieted by these trips. Carhart-Harris believes that the drugs may unlock emotion while &ldquobasically killing the ego,&rdquo allowing users to be less narrow-minded and let go of negative outlooks.

It&rsquos still not clear why such effects can have more profound long-term effects on the brain than our nightly dreams. But Carhart-Harris hopes to see more of these compounds in modern medicine. &ldquoThe way we treat psychological illnesses now is to dampen things,&rdquo he said. &ldquoWe dampen anxiety, dampen one&rsquos emotional range in the hope of curing depression, taking the sting out of what one feels.&rdquo
But some patients seem to benefit from having their emotions &ldquounlocked&rdquo instead. &ldquoIt would really suit the style of psychotherapy where we engage in a patient&rsquos history and hang-ups,&rdquo Carhart-Harris said. &ldquoInstead of putting a bandage over the exposed wound, we&rsquod be essentially loosening their minds &mdash promoting a permanent change in outlook.&rdquo

The latest research suggests that Psilocybin &mdash the active ingredient in magic mushrooms &mdash can have positive effects on brain function and emotional health for up to one month after leaving one&rsquos system.

Previously, most studies on Psilocybin have focused on the acute effects of the substance on the user. However, the study conducted by researchers from Johns Hopkins University School of Medicine, and published in the Scientific Reports journal, flipped the script and looked at the enduring impacts of the psychedelic.

&ldquoNearly all psychedelic imaging studies have been conducted during acute effects of psychedelic drugs,&rdquo explains Frederick S. Barrett, assistant professor at Johns Hopkins University School of Medicine and corresponding author of the study. &ldquoWhile acute effects of psychedelics on the brain are of course incredibly interesting, the enduring effects of psychedelic drugs on brain function have great untapped value in helping us to understand more about the brain, affect, and the treatment of psychiatric disorders.&rdquo

About the Psilocybin Study

The study &mdash titled &lsquoEmotions and Brain Function Are Altered Up to One Month After a Single High Dose of Psilocybin&rsquo &mdash looked at 12 volunteers who each received a single dose of Psilocybin. The participants underwent tests the day before taking the Psilocybin, one week after taking Psilocybin, and one month later. Each volunteer was tasked with completing three different assessments designed to quantify their ability to process emotional information (i.e. facial cues). At the same time, the research team studied their brain activity using an MRI.

Granted, the study involved only a small number of participants and relied heavily on self-reporting, but participants reported a reduction in emotional distress in the week following the administration of Psilocybin. At the one-month mark, reported emotional distress generally returned to baseline levels.


Psychedelic ‘shrooms’ may have positive long-term effects on the brain

Psychedelic mushrooms can do more than make you see the world in kaleidoscope. Research suggests they may have permanent, positive effects on the human brain.

In fact, a mind-altering compound found in some 200 species of mushroom is already being explored as a potential treatment for depression and anxiety. People who consume these mushrooms, after &ldquotrips&rdquo that can be a bit scary and unpleasant, report feeling more optimistic, less self-centred and even happier for months after the fact.

But why do these trips change the way people see the world? According to a study published this week in Human Brain Mapping, the mushroom compounds could be unlocking brain states usually only experienced when we dream, changes in activity that could help unlock permanent shifts in perspective.

The study examined brain activity in those who received injections of psilocybin, which gives &ldquoshrooms&rdquo their psychedelic punch. Despite a long history of mushroom use in spiritual practice, scientists have only recently begun to examine the brain activity of those using the compound, and this is the first study to attempt to relate the behavioural effects to biological changes.

After the injections, the 15 participants were found to have increased brain function in areas associated with emotion and memory. The effect was strikingly similar to a brain in dream sleep, according to Robin Carhart-Harris, a post-doctoral researcher in neuropsychopharmacology at Imperial College London and co-author of the study.

&ldquoYou&rsquore seeing these areas getting louder and more active,&rdquo he said. &ldquoIt&rsquos like someone&rsquos turned up the volume there, in these regions that are considered part of an emotional system in the brain. When you look at a brain during dream sleep, you see the same hyperactive emotion centres.&rdquo

In fact, administration of the drug just before or during sleep seemed to promote higher activity levels during Rapid Eye Movement sleep, when dreams occur. An intriguing finding, Carhart-Harris says, given that people tend to describe their experience on psychedelic drugs as being like &ldquoa waking dream.&rdquo It seems that the brain may literally be slipping into unconscious patterns while the user is awake.
Conversely, the subjects of the study had decreased activity in other parts of the brain areas associated with high-level cognition. &ldquoThese are the most recent parts of our brain, in an evolutionary sense,&rdquo Carhart-Harris said. &ldquoAnd we see them getting quieter and less organized.&rdquo

This dampening of one area and amplification of another could explain the &ldquomind-broadening&rdquo sensation of psychedelic drugs, he said. Unlike most recreational drugs, psychotropic mushrooms and LSD don&rsquot provide a pleasant, hedonistic reward when they&rsquore consumed. Instead, users take them very occasionally, chasing the strange neurological effects instead of any sort of high.

&ldquoExcept for some naïve users who go looking for a good time &hellip which, by the way, is not how it plays out,&rdquo Carhart-Harris said, &ldquoyou see people taking them to experience some kind of mental exploration and to try to understand themselves.&rdquo

Our firm sense of self &mdash the habits and experiences that we find integral to our personality &mdash is quieted by these trips. Carhart-Harris believes that the drugs may unlock emotion while &ldquobasically killing the ego,&rdquo allowing users to be less narrow-minded and let go of negative outlooks.

It&rsquos still not clear why such effects can have more profound long-term effects on the brain than our nightly dreams. But Carhart-Harris hopes to see more of these compounds in modern medicine. &ldquoThe way we treat psychological illnesses now is to dampen things,&rdquo he said. &ldquoWe dampen anxiety, dampen one&rsquos emotional range in the hope of curing depression, taking the sting out of what one feels.&rdquo
But some patients seem to benefit from having their emotions &ldquounlocked&rdquo instead. &ldquoIt would really suit the style of psychotherapy where we engage in a patient&rsquos history and hang-ups,&rdquo Carhart-Harris said. &ldquoInstead of putting a bandage over the exposed wound, we&rsquod be essentially loosening their minds &mdash promoting a permanent change in outlook.&rdquo

The latest research suggests that Psilocybin &mdash the active ingredient in magic mushrooms &mdash can have positive effects on brain function and emotional health for up to one month after leaving one&rsquos system.

Previously, most studies on Psilocybin have focused on the acute effects of the substance on the user. However, the study conducted by researchers from Johns Hopkins University School of Medicine, and published in the Scientific Reports journal, flipped the script and looked at the enduring impacts of the psychedelic.

&ldquoNearly all psychedelic imaging studies have been conducted during acute effects of psychedelic drugs,&rdquo explains Frederick S. Barrett, assistant professor at Johns Hopkins University School of Medicine and corresponding author of the study. &ldquoWhile acute effects of psychedelics on the brain are of course incredibly interesting, the enduring effects of psychedelic drugs on brain function have great untapped value in helping us to understand more about the brain, affect, and the treatment of psychiatric disorders.&rdquo

About the Psilocybin Study

The study &mdash titled &lsquoEmotions and Brain Function Are Altered Up to One Month After a Single High Dose of Psilocybin&rsquo &mdash looked at 12 volunteers who each received a single dose of Psilocybin. The participants underwent tests the day before taking the Psilocybin, one week after taking Psilocybin, and one month later. Each volunteer was tasked with completing three different assessments designed to quantify their ability to process emotional information (i.e. facial cues). At the same time, the research team studied their brain activity using an MRI.

Granted, the study involved only a small number of participants and relied heavily on self-reporting, but participants reported a reduction in emotional distress in the week following the administration of Psilocybin. At the one-month mark, reported emotional distress generally returned to baseline levels.


Psychedelic ‘shrooms’ may have positive long-term effects on the brain

Psychedelic mushrooms can do more than make you see the world in kaleidoscope. Research suggests they may have permanent, positive effects on the human brain.

In fact, a mind-altering compound found in some 200 species of mushroom is already being explored as a potential treatment for depression and anxiety. People who consume these mushrooms, after &ldquotrips&rdquo that can be a bit scary and unpleasant, report feeling more optimistic, less self-centred and even happier for months after the fact.

But why do these trips change the way people see the world? According to a study published this week in Human Brain Mapping, the mushroom compounds could be unlocking brain states usually only experienced when we dream, changes in activity that could help unlock permanent shifts in perspective.

The study examined brain activity in those who received injections of psilocybin, which gives &ldquoshrooms&rdquo their psychedelic punch. Despite a long history of mushroom use in spiritual practice, scientists have only recently begun to examine the brain activity of those using the compound, and this is the first study to attempt to relate the behavioural effects to biological changes.

After the injections, the 15 participants were found to have increased brain function in areas associated with emotion and memory. The effect was strikingly similar to a brain in dream sleep, according to Robin Carhart-Harris, a post-doctoral researcher in neuropsychopharmacology at Imperial College London and co-author of the study.

&ldquoYou&rsquore seeing these areas getting louder and more active,&rdquo he said. &ldquoIt&rsquos like someone&rsquos turned up the volume there, in these regions that are considered part of an emotional system in the brain. When you look at a brain during dream sleep, you see the same hyperactive emotion centres.&rdquo

In fact, administration of the drug just before or during sleep seemed to promote higher activity levels during Rapid Eye Movement sleep, when dreams occur. An intriguing finding, Carhart-Harris says, given that people tend to describe their experience on psychedelic drugs as being like &ldquoa waking dream.&rdquo It seems that the brain may literally be slipping into unconscious patterns while the user is awake.
Conversely, the subjects of the study had decreased activity in other parts of the brain areas associated with high-level cognition. &ldquoThese are the most recent parts of our brain, in an evolutionary sense,&rdquo Carhart-Harris said. &ldquoAnd we see them getting quieter and less organized.&rdquo

This dampening of one area and amplification of another could explain the &ldquomind-broadening&rdquo sensation of psychedelic drugs, he said. Unlike most recreational drugs, psychotropic mushrooms and LSD don&rsquot provide a pleasant, hedonistic reward when they&rsquore consumed. Instead, users take them very occasionally, chasing the strange neurological effects instead of any sort of high.

&ldquoExcept for some naïve users who go looking for a good time &hellip which, by the way, is not how it plays out,&rdquo Carhart-Harris said, &ldquoyou see people taking them to experience some kind of mental exploration and to try to understand themselves.&rdquo

Our firm sense of self &mdash the habits and experiences that we find integral to our personality &mdash is quieted by these trips. Carhart-Harris believes that the drugs may unlock emotion while &ldquobasically killing the ego,&rdquo allowing users to be less narrow-minded and let go of negative outlooks.

It&rsquos still not clear why such effects can have more profound long-term effects on the brain than our nightly dreams. But Carhart-Harris hopes to see more of these compounds in modern medicine. &ldquoThe way we treat psychological illnesses now is to dampen things,&rdquo he said. &ldquoWe dampen anxiety, dampen one&rsquos emotional range in the hope of curing depression, taking the sting out of what one feels.&rdquo
But some patients seem to benefit from having their emotions &ldquounlocked&rdquo instead. &ldquoIt would really suit the style of psychotherapy where we engage in a patient&rsquos history and hang-ups,&rdquo Carhart-Harris said. &ldquoInstead of putting a bandage over the exposed wound, we&rsquod be essentially loosening their minds &mdash promoting a permanent change in outlook.&rdquo

The latest research suggests that Psilocybin &mdash the active ingredient in magic mushrooms &mdash can have positive effects on brain function and emotional health for up to one month after leaving one&rsquos system.

Previously, most studies on Psilocybin have focused on the acute effects of the substance on the user. However, the study conducted by researchers from Johns Hopkins University School of Medicine, and published in the Scientific Reports journal, flipped the script and looked at the enduring impacts of the psychedelic.

&ldquoNearly all psychedelic imaging studies have been conducted during acute effects of psychedelic drugs,&rdquo explains Frederick S. Barrett, assistant professor at Johns Hopkins University School of Medicine and corresponding author of the study. &ldquoWhile acute effects of psychedelics on the brain are of course incredibly interesting, the enduring effects of psychedelic drugs on brain function have great untapped value in helping us to understand more about the brain, affect, and the treatment of psychiatric disorders.&rdquo

About the Psilocybin Study

The study &mdash titled &lsquoEmotions and Brain Function Are Altered Up to One Month After a Single High Dose of Psilocybin&rsquo &mdash looked at 12 volunteers who each received a single dose of Psilocybin. The participants underwent tests the day before taking the Psilocybin, one week after taking Psilocybin, and one month later. Each volunteer was tasked with completing three different assessments designed to quantify their ability to process emotional information (i.e. facial cues). At the same time, the research team studied their brain activity using an MRI.

Granted, the study involved only a small number of participants and relied heavily on self-reporting, but participants reported a reduction in emotional distress in the week following the administration of Psilocybin. At the one-month mark, reported emotional distress generally returned to baseline levels.


Psychedelic ‘shrooms’ may have positive long-term effects on the brain

Psychedelic mushrooms can do more than make you see the world in kaleidoscope. Research suggests they may have permanent, positive effects on the human brain.

In fact, a mind-altering compound found in some 200 species of mushroom is already being explored as a potential treatment for depression and anxiety. People who consume these mushrooms, after &ldquotrips&rdquo that can be a bit scary and unpleasant, report feeling more optimistic, less self-centred and even happier for months after the fact.

But why do these trips change the way people see the world? According to a study published this week in Human Brain Mapping, the mushroom compounds could be unlocking brain states usually only experienced when we dream, changes in activity that could help unlock permanent shifts in perspective.

The study examined brain activity in those who received injections of psilocybin, which gives &ldquoshrooms&rdquo their psychedelic punch. Despite a long history of mushroom use in spiritual practice, scientists have only recently begun to examine the brain activity of those using the compound, and this is the first study to attempt to relate the behavioural effects to biological changes.

After the injections, the 15 participants were found to have increased brain function in areas associated with emotion and memory. The effect was strikingly similar to a brain in dream sleep, according to Robin Carhart-Harris, a post-doctoral researcher in neuropsychopharmacology at Imperial College London and co-author of the study.

&ldquoYou&rsquore seeing these areas getting louder and more active,&rdquo he said. &ldquoIt&rsquos like someone&rsquos turned up the volume there, in these regions that are considered part of an emotional system in the brain. When you look at a brain during dream sleep, you see the same hyperactive emotion centres.&rdquo

In fact, administration of the drug just before or during sleep seemed to promote higher activity levels during Rapid Eye Movement sleep, when dreams occur. An intriguing finding, Carhart-Harris says, given that people tend to describe their experience on psychedelic drugs as being like &ldquoa waking dream.&rdquo It seems that the brain may literally be slipping into unconscious patterns while the user is awake.
Conversely, the subjects of the study had decreased activity in other parts of the brain areas associated with high-level cognition. &ldquoThese are the most recent parts of our brain, in an evolutionary sense,&rdquo Carhart-Harris said. &ldquoAnd we see them getting quieter and less organized.&rdquo

This dampening of one area and amplification of another could explain the &ldquomind-broadening&rdquo sensation of psychedelic drugs, he said. Unlike most recreational drugs, psychotropic mushrooms and LSD don&rsquot provide a pleasant, hedonistic reward when they&rsquore consumed. Instead, users take them very occasionally, chasing the strange neurological effects instead of any sort of high.

&ldquoExcept for some naïve users who go looking for a good time &hellip which, by the way, is not how it plays out,&rdquo Carhart-Harris said, &ldquoyou see people taking them to experience some kind of mental exploration and to try to understand themselves.&rdquo

Our firm sense of self &mdash the habits and experiences that we find integral to our personality &mdash is quieted by these trips. Carhart-Harris believes that the drugs may unlock emotion while &ldquobasically killing the ego,&rdquo allowing users to be less narrow-minded and let go of negative outlooks.

It&rsquos still not clear why such effects can have more profound long-term effects on the brain than our nightly dreams. But Carhart-Harris hopes to see more of these compounds in modern medicine. &ldquoThe way we treat psychological illnesses now is to dampen things,&rdquo he said. &ldquoWe dampen anxiety, dampen one&rsquos emotional range in the hope of curing depression, taking the sting out of what one feels.&rdquo
But some patients seem to benefit from having their emotions &ldquounlocked&rdquo instead. &ldquoIt would really suit the style of psychotherapy where we engage in a patient&rsquos history and hang-ups,&rdquo Carhart-Harris said. &ldquoInstead of putting a bandage over the exposed wound, we&rsquod be essentially loosening their minds &mdash promoting a permanent change in outlook.&rdquo

The latest research suggests that Psilocybin &mdash the active ingredient in magic mushrooms &mdash can have positive effects on brain function and emotional health for up to one month after leaving one&rsquos system.

Previously, most studies on Psilocybin have focused on the acute effects of the substance on the user. However, the study conducted by researchers from Johns Hopkins University School of Medicine, and published in the Scientific Reports journal, flipped the script and looked at the enduring impacts of the psychedelic.

&ldquoNearly all psychedelic imaging studies have been conducted during acute effects of psychedelic drugs,&rdquo explains Frederick S. Barrett, assistant professor at Johns Hopkins University School of Medicine and corresponding author of the study. &ldquoWhile acute effects of psychedelics on the brain are of course incredibly interesting, the enduring effects of psychedelic drugs on brain function have great untapped value in helping us to understand more about the brain, affect, and the treatment of psychiatric disorders.&rdquo

About the Psilocybin Study

The study &mdash titled &lsquoEmotions and Brain Function Are Altered Up to One Month After a Single High Dose of Psilocybin&rsquo &mdash looked at 12 volunteers who each received a single dose of Psilocybin. The participants underwent tests the day before taking the Psilocybin, one week after taking Psilocybin, and one month later. Each volunteer was tasked with completing three different assessments designed to quantify their ability to process emotional information (i.e. facial cues). At the same time, the research team studied their brain activity using an MRI.

Granted, the study involved only a small number of participants and relied heavily on self-reporting, but participants reported a reduction in emotional distress in the week following the administration of Psilocybin. At the one-month mark, reported emotional distress generally returned to baseline levels.


Psychedelic ‘shrooms’ may have positive long-term effects on the brain

Psychedelic mushrooms can do more than make you see the world in kaleidoscope. Research suggests they may have permanent, positive effects on the human brain.

In fact, a mind-altering compound found in some 200 species of mushroom is already being explored as a potential treatment for depression and anxiety. People who consume these mushrooms, after &ldquotrips&rdquo that can be a bit scary and unpleasant, report feeling more optimistic, less self-centred and even happier for months after the fact.

But why do these trips change the way people see the world? According to a study published this week in Human Brain Mapping, the mushroom compounds could be unlocking brain states usually only experienced when we dream, changes in activity that could help unlock permanent shifts in perspective.

The study examined brain activity in those who received injections of psilocybin, which gives &ldquoshrooms&rdquo their psychedelic punch. Despite a long history of mushroom use in spiritual practice, scientists have only recently begun to examine the brain activity of those using the compound, and this is the first study to attempt to relate the behavioural effects to biological changes.

After the injections, the 15 participants were found to have increased brain function in areas associated with emotion and memory. The effect was strikingly similar to a brain in dream sleep, according to Robin Carhart-Harris, a post-doctoral researcher in neuropsychopharmacology at Imperial College London and co-author of the study.

&ldquoYou&rsquore seeing these areas getting louder and more active,&rdquo he said. &ldquoIt&rsquos like someone&rsquos turned up the volume there, in these regions that are considered part of an emotional system in the brain. When you look at a brain during dream sleep, you see the same hyperactive emotion centres.&rdquo

In fact, administration of the drug just before or during sleep seemed to promote higher activity levels during Rapid Eye Movement sleep, when dreams occur. An intriguing finding, Carhart-Harris says, given that people tend to describe their experience on psychedelic drugs as being like &ldquoa waking dream.&rdquo It seems that the brain may literally be slipping into unconscious patterns while the user is awake.
Conversely, the subjects of the study had decreased activity in other parts of the brain areas associated with high-level cognition. &ldquoThese are the most recent parts of our brain, in an evolutionary sense,&rdquo Carhart-Harris said. &ldquoAnd we see them getting quieter and less organized.&rdquo

This dampening of one area and amplification of another could explain the &ldquomind-broadening&rdquo sensation of psychedelic drugs, he said. Unlike most recreational drugs, psychotropic mushrooms and LSD don&rsquot provide a pleasant, hedonistic reward when they&rsquore consumed. Instead, users take them very occasionally, chasing the strange neurological effects instead of any sort of high.

&ldquoExcept for some naïve users who go looking for a good time &hellip which, by the way, is not how it plays out,&rdquo Carhart-Harris said, &ldquoyou see people taking them to experience some kind of mental exploration and to try to understand themselves.&rdquo

Our firm sense of self &mdash the habits and experiences that we find integral to our personality &mdash is quieted by these trips. Carhart-Harris believes that the drugs may unlock emotion while &ldquobasically killing the ego,&rdquo allowing users to be less narrow-minded and let go of negative outlooks.

It&rsquos still not clear why such effects can have more profound long-term effects on the brain than our nightly dreams. But Carhart-Harris hopes to see more of these compounds in modern medicine. &ldquoThe way we treat psychological illnesses now is to dampen things,&rdquo he said. &ldquoWe dampen anxiety, dampen one&rsquos emotional range in the hope of curing depression, taking the sting out of what one feels.&rdquo
But some patients seem to benefit from having their emotions &ldquounlocked&rdquo instead. &ldquoIt would really suit the style of psychotherapy where we engage in a patient&rsquos history and hang-ups,&rdquo Carhart-Harris said. &ldquoInstead of putting a bandage over the exposed wound, we&rsquod be essentially loosening their minds &mdash promoting a permanent change in outlook.&rdquo

The latest research suggests that Psilocybin &mdash the active ingredient in magic mushrooms &mdash can have positive effects on brain function and emotional health for up to one month after leaving one&rsquos system.

Previously, most studies on Psilocybin have focused on the acute effects of the substance on the user. However, the study conducted by researchers from Johns Hopkins University School of Medicine, and published in the Scientific Reports journal, flipped the script and looked at the enduring impacts of the psychedelic.

&ldquoNearly all psychedelic imaging studies have been conducted during acute effects of psychedelic drugs,&rdquo explains Frederick S. Barrett, assistant professor at Johns Hopkins University School of Medicine and corresponding author of the study. &ldquoWhile acute effects of psychedelics on the brain are of course incredibly interesting, the enduring effects of psychedelic drugs on brain function have great untapped value in helping us to understand more about the brain, affect, and the treatment of psychiatric disorders.&rdquo

About the Psilocybin Study

The study &mdash titled &lsquoEmotions and Brain Function Are Altered Up to One Month After a Single High Dose of Psilocybin&rsquo &mdash looked at 12 volunteers who each received a single dose of Psilocybin. The participants underwent tests the day before taking the Psilocybin, one week after taking Psilocybin, and one month later. Each volunteer was tasked with completing three different assessments designed to quantify their ability to process emotional information (i.e. facial cues). At the same time, the research team studied their brain activity using an MRI.

Granted, the study involved only a small number of participants and relied heavily on self-reporting, but participants reported a reduction in emotional distress in the week following the administration of Psilocybin. At the one-month mark, reported emotional distress generally returned to baseline levels.


Psychedelic ‘shrooms’ may have positive long-term effects on the brain

Psychedelic mushrooms can do more than make you see the world in kaleidoscope. Research suggests they may have permanent, positive effects on the human brain.

In fact, a mind-altering compound found in some 200 species of mushroom is already being explored as a potential treatment for depression and anxiety. People who consume these mushrooms, after &ldquotrips&rdquo that can be a bit scary and unpleasant, report feeling more optimistic, less self-centred and even happier for months after the fact.

But why do these trips change the way people see the world? According to a study published this week in Human Brain Mapping, the mushroom compounds could be unlocking brain states usually only experienced when we dream, changes in activity that could help unlock permanent shifts in perspective.

The study examined brain activity in those who received injections of psilocybin, which gives &ldquoshrooms&rdquo their psychedelic punch. Despite a long history of mushroom use in spiritual practice, scientists have only recently begun to examine the brain activity of those using the compound, and this is the first study to attempt to relate the behavioural effects to biological changes.

After the injections, the 15 participants were found to have increased brain function in areas associated with emotion and memory. The effect was strikingly similar to a brain in dream sleep, according to Robin Carhart-Harris, a post-doctoral researcher in neuropsychopharmacology at Imperial College London and co-author of the study.

&ldquoYou&rsquore seeing these areas getting louder and more active,&rdquo he said. &ldquoIt&rsquos like someone&rsquos turned up the volume there, in these regions that are considered part of an emotional system in the brain. When you look at a brain during dream sleep, you see the same hyperactive emotion centres.&rdquo

In fact, administration of the drug just before or during sleep seemed to promote higher activity levels during Rapid Eye Movement sleep, when dreams occur. An intriguing finding, Carhart-Harris says, given that people tend to describe their experience on psychedelic drugs as being like &ldquoa waking dream.&rdquo It seems that the brain may literally be slipping into unconscious patterns while the user is awake.
Conversely, the subjects of the study had decreased activity in other parts of the brain areas associated with high-level cognition. &ldquoThese are the most recent parts of our brain, in an evolutionary sense,&rdquo Carhart-Harris said. &ldquoAnd we see them getting quieter and less organized.&rdquo

This dampening of one area and amplification of another could explain the &ldquomind-broadening&rdquo sensation of psychedelic drugs, he said. Unlike most recreational drugs, psychotropic mushrooms and LSD don&rsquot provide a pleasant, hedonistic reward when they&rsquore consumed. Instead, users take them very occasionally, chasing the strange neurological effects instead of any sort of high.

&ldquoExcept for some naïve users who go looking for a good time &hellip which, by the way, is not how it plays out,&rdquo Carhart-Harris said, &ldquoyou see people taking them to experience some kind of mental exploration and to try to understand themselves.&rdquo

Our firm sense of self &mdash the habits and experiences that we find integral to our personality &mdash is quieted by these trips. Carhart-Harris believes that the drugs may unlock emotion while &ldquobasically killing the ego,&rdquo allowing users to be less narrow-minded and let go of negative outlooks.

It&rsquos still not clear why such effects can have more profound long-term effects on the brain than our nightly dreams. But Carhart-Harris hopes to see more of these compounds in modern medicine. &ldquoThe way we treat psychological illnesses now is to dampen things,&rdquo he said. &ldquoWe dampen anxiety, dampen one&rsquos emotional range in the hope of curing depression, taking the sting out of what one feels.&rdquo
But some patients seem to benefit from having their emotions &ldquounlocked&rdquo instead. &ldquoIt would really suit the style of psychotherapy where we engage in a patient&rsquos history and hang-ups,&rdquo Carhart-Harris said. &ldquoInstead of putting a bandage over the exposed wound, we&rsquod be essentially loosening their minds &mdash promoting a permanent change in outlook.&rdquo

The latest research suggests that Psilocybin &mdash the active ingredient in magic mushrooms &mdash can have positive effects on brain function and emotional health for up to one month after leaving one&rsquos system.

Previously, most studies on Psilocybin have focused on the acute effects of the substance on the user. However, the study conducted by researchers from Johns Hopkins University School of Medicine, and published in the Scientific Reports journal, flipped the script and looked at the enduring impacts of the psychedelic.

&ldquoNearly all psychedelic imaging studies have been conducted during acute effects of psychedelic drugs,&rdquo explains Frederick S. Barrett, assistant professor at Johns Hopkins University School of Medicine and corresponding author of the study. &ldquoWhile acute effects of psychedelics on the brain are of course incredibly interesting, the enduring effects of psychedelic drugs on brain function have great untapped value in helping us to understand more about the brain, affect, and the treatment of psychiatric disorders.&rdquo

About the Psilocybin Study

The study &mdash titled &lsquoEmotions and Brain Function Are Altered Up to One Month After a Single High Dose of Psilocybin&rsquo &mdash looked at 12 volunteers who each received a single dose of Psilocybin. The participants underwent tests the day before taking the Psilocybin, one week after taking Psilocybin, and one month later. Each volunteer was tasked with completing three different assessments designed to quantify their ability to process emotional information (i.e. facial cues). At the same time, the research team studied their brain activity using an MRI.

Granted, the study involved only a small number of participants and relied heavily on self-reporting, but participants reported a reduction in emotional distress in the week following the administration of Psilocybin. At the one-month mark, reported emotional distress generally returned to baseline levels.